Xevo TQ-S micro

Specifications

API sources and ionization modes	High performance ZSpray dual-orthogonal API sources: 1) Multi-mode source – tool-free ESI/APCI/ESCi™* (standard) NB – Dedicated APCI requires an additional probe (optional) 2) UniSpray™ ion source (optional) 3) Tool-free APCI probe (optional) 4) nanoFlow™ ESI source* (optional) 5) ASAP* (optional) 6) APGC ion source* (optional) 7) ionKey™/MS™ source* (optional) Optimized gas flow dynamics for efficient ESI desolvation Tool-free source exchange Vacuum isolation valve Tool-free access to customer serviceable elements Plug-and-play probes De-clustering cone gas Software control of gas flows and heating elements
UniSpray ion source option	UniSpray is an ionization technique designed to broaden the scope of compounds which can be analyzed in a single run, including those which typically optimize in ESI, APCI or APPI. Enhanced ionization efficiency and desolvation allow the potential to combine several methodologies into one, or simply enable the operator to keep the same source for multiple methods, requiring less time performing set-up and routine maintenance, and more time delivering results
Ion source transfer optics	StepWave ion transfer optics delivering class leading UPLC™-MS/MS sensitivity. The unique off-axis design dramatically increases the efficiency of ion transfer from the ion source to the quadrupole MS analyzer at the same time as actively eliminating undesirable neutral contaminants
Mass analyzer	Two high resolution, high stability quadrupole analyzers (MS1/MS2), plus pre-filters to maximize resolution and transmission while preventing contamination of the main analyzers
Collision cell	T-Wave™ enabled for optimal MS/MS performance at high data acquisition rates
Detector	Low noise, off axis, long life photomultiplier detector
Vacuum system	One split-flow air-cooled vacuum turbomolecular pump evacuating the source and analyzer One vacuum backing pump
Dimensions	Width: 35.6 cm (14.0 in) Height: 60.0 cm (23.6 in) Depth: 93 cm (36.6 in)
Regulatory approvals/marks	CE, CB, NRTL (CAN/US), RCM

Software	Systems supported on waters_connect and MassLynx™ version 4.2 or later
System setup and method development	System parameter checking and alerts Integrated sample/calibrant delivery system + programmable divert valve Automated mass calibration Automated sample tuning Automated MRM method development UPLC-MS/MS System Check – automated on-column performance test
Automated MRM scheduling (acquisition window assignment)	Dwell time, inter-channel delay time, and inter-scan delay time for individual channels in a multiple MRM experiment can be automatically assigned (using the Auto-Dwell feature) to ensure that the optimal number of MRM data points per chromatographic peak is acquired. The Auto-Dwell feature can dynamically optimize MRM cycle times to accommodate retention time windows that either partially or completely overlap.This greatly simplifies MRM method creation, irrespective of the number of compounds in a single assay, while at the same time ensuring the very best quantitative performance for every experiment
waters_connect Software	The waters_connect Software provides a modern user experience with a HUB design and apps that provide a consistent connected user experience across all applications. It is built for applications with convenient access to scientific apps allowing accelerated time-to-results and result quality. There are common utilities that complete the end-toend workflow and help increase productivity and efficiency. Confidently report results with accurate, reliable, regulation-standard data from application-focused quantitative workflows with built in traceability for utmost integrity

Acquisition modes

Full scan MS

Product ion scan

Precursor ion scan

Constant neutral loss

Multiple reaction monitoring (MRM)

Simultaneous full scan and MRM (RADAR)

RADAR

An information rich acquisition approach that allows you to collect highly specific quantitative data for target compounds while providing the ability to visualize all other components

Mass range

2 to 2048 m/z

Compare Xevo TQ Systems

	Xevo TQ-S cronos Xevo TQ-S cronos	Xevo TQ-S micro Xevo TQ-S micro	Xevo TQ-XS Xevo TQ-XS	Xevo TQ Absolute Xevo TQ Absolute
Dimensions (w x h x d)	Dimensions (w x h x d)	Dimensions (w x h x d)	Dimensions (w x h x d)	Dimensions (w x h x d)
Dimensions (w x h x d)	35.6 x 60 x 93 cm	35.6 x 60 x 93 cm	61 x 70.7 x 99.5 cm	43 x 79 x 96 cm
Sensitivity key	Sensitivity key	Sensitivity key	Sensitivity key	Sensitivity key
Sensitivity key	★★	★★★	★★★★	★★★★★
Mass range	Mass range	Mass range	Mass range	Mass range
Mass range	2 to 2048 m/z	2 to 2048 m/z	2 to 2048 m/z	2 to 2048 m/z
Chromatographic configuration compatibility	Chromatographic configuration compatibility	Chromatographic configuration compatibility	Chromatographic configuration compatibility	Chromatographic configuration compatibility
Chromatographic configuration compatibility	ACQUITY Arc* ACQUITY Premier ACQUITY UPC2* ACQUITY UPLC ACQUITY UPLC M-Class*	ACQUITY Premier ACQUITY UPC2* ACQUITY UPLC ACQUITY UPLC M-Class* APGC*	ACQUITY Premier ACQUITY UPC2* ACQUITY UPLC ACQUITY UPLC M-Class* APGC*	ACQUITY Premier ACQUITY UPLC ACQUITY UPLC M-Class* APGC*
Ion sources compatibility	Ion sources compatibility	Ion sources compatibility	Ion sources compatibility	Ion sources compatibility
Ion sources compatibility	APCI ASAP* ESCi* ESI UniSpray	APCI APGC* ASAP* ESCi* ESI ionKey* Nanoflow* UniSpray	APCI APGC* ASAP* ESCi* ESI ionKey* Nanoflow* UniSpray	APCI APGC* ASAP* DESI XS* ESCi* ESI Nanoflow* UniSpray
Acquisition modes	Acquisition modes	Acquisition modes	Acquisition modes	Acquisition modes
Acquisition modes	Full scan Product scan Precursor ion scan Constant neutral loss scan Multiple reaction monitoring (MRM) Simultaneous Full Scan and MRM (RADAR)	Full scan Product scan Precursor ion scan Constant neutral loss scan Multiple reaction monitoring (MRM) Simultaneous Full Scan and MRM (RADAR)	Full scan Product scan Precursor ion scan Constant neutral loss scan Multiple reaction monitoring (MRM) Simultaneous Full Scan and MRM (RADAR)	Full scan Product scan Precursor ion scan Constant neutral loss scan Multiple reaction monitoring (MRM) Simultaneous Full Scan and MRM (RADAR)
Detector **	Detector **	Detector **	Detector **	Detector **
Detector **	Low noise, off axis, long life photomultiplier**	Low noise, off axis, long life photomultiplier**	Low noise, off axis, long life photomultiplier**	Low noise, off axis, long life photomultiplier**
Ion source transfer optics	Ion source transfer optics	Ion source transfer optics	Ion source transfer optics	Ion source transfer optics
Ion source transfer optics	StepWave	StepWave	StepWave XS	StepWave XS
MRM speed	MRM speed	MRM speed	MRM speed	MRM speed
MRM speed	555 MRM/ sec	555 MRM/ sec	500 MRM/ sec	500 MRM/ sec
Regulatory approval ***	Regulatory approval ***	Regulatory approval ***	Regulatory approval ***	Regulatory approval ***
Regulatory approval ***
Third party software interfaces	Third party software interfaces	Third party software interfaces	Third party software interfaces	Third party software interfaces
Third party software interfaces	LIMS interface MassLynx SkyLine interface	LIMS interface MassLynx SkyLine interface	LIMS interface MassLynx SkyLine interface	LIMS interface MassLynx SkyLine interface
MassLynx security	MassLynx security	MassLynx security	MassLynx security	MassLynx security
MassLynx security	Yes	Yes	Yes	Yes
Software options	Software options	Software options	Software options	Software options
Software options	MassLynx v4.2 waters_connect for Quantitation	MassLynx v4.2 waters_connect for Quantitation	MassLynx v4.2 waters_connect for Quantitation	MassLynx v4.2 waters_connect for Quantitation

* Not available with waters_connect

** Less than 1% of Waters’ tandem quadrupole mass spectrometers require a detector replacement on an annual basis. [Source: Waters’ internal data on the service history of its tandem quadrupole mass spectrometers launched between 2006 and 2022]

*** Regulated approval marks include CE, CB, NRTL (Canada/USA), RCM

Overview

Reliable performance: Achieve your objectives in full with operational performance you can rely on.
Maximize uptime Get the most from your instrument and avoid time-consuming repair visits.
Achieve more with less: Productivity advances to maximize lab capacity. Improve your analytical capabilities and capacity with minimal impact on your coveted bench-space.
Optimum productivity with flexible software options: Achieve the ultimate flexibility to choose the right solution for your lab with our flexible software options for quantitation - the waters_connect and MassLynx software platforms.
Flexibility to meet your analytical needs: Change the chromatographic inlets or ionization sources to extend your analytical capacity and meet changing demands.

Recommended Use: Laboratory workhorse, offering best value performance per square inch of benchspace with unrivalled flexibility to meet your changing, growing, or unexpected analytical demands.

Features Header

Reliable performance

Achieve your objectives in full with operational performance you can rely on. A Xevo TQ-S micro study analyzing mycotoxins in wheat flour (a complex matrix that can contaminate LC-MS instrumentation) showed consistent performance over 5 days of continuous use with 1,000 injections and only 5-9% relative standard deviation (RSD) for peak areas.

Maximize uptime

Get the most from your instrument and avoid time-consuming repair visits. Customers using the Xevo TQ-S micro will on average not need an unplanned service visit during the warranty period and for 3 years after¹

Ensure your laboratory runs efficiently and is ready to address the opportunities of tomorrow with Waters comprehensive analytical solutions with expert training (APS) and flexible and cost-effective solutions to advance your business with system service (FlexCHOICE), trade-ins, and technological upgrades (FlexUP)

^₁_{Source Waters internal service data on unplanned service visits for Xevo TQ-S micro issues that occur globally. Note that planned visits for regular scheduled Performance Maintenance are recommended to ensure trouble-free operation}

Achieve more with less

The Xevo TQ-S micro is 2-3X narrower than other instruments in its class, reducing laboratory space overhead costs. Use of the Xevo TQ-S micro provides up to 34% lower electricity power consumption and associated heat production than other instruments in its class.

Ensure optimum productivity with flexible software options

Achieve the ultimate flexibility to choose the right solution for your lab with our flexible software options for quantitation - the waters_connect and MassLynx software platforms. Our modern, app-based software platform waters_connect delivers efficiency and usability benefits, including the unique Exception Focused Review (XFR) functionality that can save up to 50% of your data review time and ensures your lab is as productive as possible. Meanwhile, our tried, well-established MassLynx Software package delivers superior versatility and flexibility across all application areas.

Flexibility to meet your analytical needs

With the most commonly used atmospheric pressure ionization source of ESI as standard, simply change the chromatographic inlet or ionization source to extend your analytical capacity and meet changing demands.

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Xevo TQ-S micro Triple Quadrupole Mass Spectrometer

Defining compact performance - robust sensitivity beyond expectation

Specifications

Compare Xevo TQ Systems

Xevo TQ-S cronos

Xevo TQ-XS

Xevo TQ Absolute