Discovery proteomics helps scientists understand the important functional roles these complex macromolecules play. Accurately identifying proteins differentially expressed in disease states can be potentially translated to functional biomarkers. Proteomics is also an important component of systems biology approaches, and multi-omics analysis helps validate findings to better understand metabolic and signaling processes.
To more accurately understand the proteome, Waters pioneered Data Independent Acquisition (DIA) strategies to improve the quantitative analysis of ‘bottom-up’ non-labeled proteomics methods while generating peptide fragment spectra for all detectible species. With Waters high resolution mass spectrometry technologies, high peak capacity chromatography systems, Progenesis Software, and DIA methods, your lab can dig even deeper into the proteome.
White Paper: Considerations for Selecting the Optimal Stationary Phases for Proteomic Trap-and-Elute Nanochromatography